Which neurotransmitter is most closely associated with vomiting? A. Noradrenaline B. Calcitonin gene-related peptide (CGRP) C. Acetylcholine (Ach) D. Substance P E. Vasoactive intestinal peptide The answer is D. Substance P (SP)–neurokinin-1 (NK1) receptor pathways are involved in the pathophysiology of emesis and depression. It is a potent vaso-dilator mediated by endothelial release of NO. […]
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